課程資訊
課程名稱
醫用微感測器
Medical Microsensor 
開課學期
112-2 
授課對象
工學院  醫學工程學研究所  
授課教師
林啟萬 
課號
DBME5042 
課程識別碼
528 U0630 
班次
 
學分
3.0 
全/半年
半年 
必/選修
選修 
上課時間
星期二2,3,4(9:10~12:10) 
上課地點
 
備註
本課程中文授課,使用英文教科書。上課教室:永齡414室。
限學士班三年級以上 且 限本系所學生(含輔系、雙修生)
總人數上限:20人 
 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
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課程概述

The continuous developments in genomics, proteomics, and metabolomics will help to drive the use of micro/nano sensor technologies for personalized medicine or companion medicine. This course aims to provide the necessary background knowledge for multi-disciplinary students on both sides of medical applications and engineering approaches. Both physical-based and bio-chemical-based micro-sensors will be covered in the lectures. 

課程目標
1. Prepare students for the multi-disciplinary natures of micro-sensors with physical & chemical fundamentals.
2. Design and fabrication processes of integrated sensor systems for clinical applications.
3. Critical assessments of the static and dynamic performance of biomedical sensors.  
課程要求
1. General background in Physics, Biology, and Engineering Mathematics.
2.Reading assignments before each class and participate in active discussion.
3. Homework assignment 
預期每週課後學習時數
3-6 hours 
Office Hours
另約時間 備註: Please send request for appointment. 
指定閱讀
Reading assignments as listed each week 
參考書目
1. Fundamentals of Microfabrication, Marc Madou, CRC Press
2. Microsensors principles and applications, Julian W. Gardner, Wiely, Inc.
3. Introduction to bioanalytical sensors, Alice J. Cunningham, Wiely, Inc.
4. Microreactors new technology for modern chemistry, Wolfgang Ehrfeld, Volker Hesel, Holger Lowe, Wiley-VCH, 2000.
5. Biomedical Sensors and Instruments 2nd Ed. CRC Press Tatsuo Tagawa; Toshiyo Tamura; P. Ake Oberg;
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
Homeworks 
20% 
Multiple homework assignments 
2. 
Midterm 
35% 
First part of Physical sensors 
3. 
Final 
35% 
Second part of the Biosensors 
4. 
Special report 
10% 
Select one topic from the course lecture and work on a special project for biomedical application. 
 
針對學生困難提供學生調整方式
 
上課形式
以錄音輔助
作業繳交方式
延長作業繳交期限, 學生與授課老師協議改以其他形式呈現
考試形式
其他
由師生雙方議定
課程進度
週次
日期
單元主題
第1週
02/20  Introduction – Types of Sensors Used in Medical & Healthcare 
第2週
02/27  Basics of Medical Measurements 
第3週
03/05  Physical sensors (I)–Bio-potential/Current 
第4週
03/12  Physical sensors (II) – Pressure/Force/Mass 
第5週
03/19  Physical sensors (III) – Flow/Velocity/Volume 
第6週
03/26  Physical sensors (IV) - Temperature 
第7週
04/02  Physical sensors (V) - Optics 
第8週
04/09  Mid-term 
第9週
04/16  Chemical sensors (I) – Biosensors 
第10週
04/23  Chemical Sensors (II) – Electrical-based impedance, EC 
第11週
04/30  Chemical Sensors (III) – Mechanical-based QCM, Cantilever 
第12週
05/07  Chemical Sensors (IV) – Optical-based Angle & Intensity SPR 
第13週
05/14  Chemical Sensors (V) – Optical-based Phase SPR 
第14週
05/21  Chemical Sensors (VI) – Fluorescent/Life time/Resonant 
第15週
05/28  Chemical Sensors (VII) – Gene/Protein/Cell-Chip, Lab-on-chip, Smart Sensor Networks 
第16週
06/04  Final